COST Action D38

Metal-Based Systems for Molecular Imaging Applications

Working Groups 2 and 6 Joint Meeting - March 24-26, 2011

Molecular Biotechnology Center, University of Torino
Keplero & Leonardo Rooms

Local organizers

• Mauro Botta (Universitá del Piemonte Orientale)
• Enzo Terreno (Universitá di Torino)

Preliminary SCIENTIFIC PROGRAM

• THURSDAY, 24^th March 2011
• • 16:30-18.00 : Registration
  • 18.00 : Opening welcome
  • 18.15-19.00 : Plenary I
    "Gadolinium-based Contrast Materials: what we have, what we need" - Francesco Sardanelli (Policlinico San Donato and University of Milan)
  • 20:00 : Dinner
  
  
• FRIDAY, 25^th March 2011
  • Chairman: Lothar Helm
  • • 9:00-9:25 "Lanthanide DOTA-Like Complexes Containing a Picolinate Pendant: Synthesis, Solution Structure and Dynamics, Photophysical Properties and Kinetic Studies" - Carlos Platas Iglesias
    • 9:25-9:50 "Dynamics of the Carboxylates in Ln-DOTA Complexes studied by ¹⁷O NMR and DFT calculations" - Florian Mayer
    • 9:50-10:15 "Interaction of Gd³⁺ chelates with Human Serum Albumin as studied by ¹H NMR STD techniques, relaxometry and theoretical modelling techniques - Carlos F.G.C. Geraldes
    • 10:10-10:35 "Lanthanide(III)- and some divalent metal complexes formed with the new heptadentate ligand PTIDTA: Equilibrium, Relaxation and Structural Properties" - Zsolt Baranyai
  • 10:35-11:00 Coffee break
  • Chairman: Éva T�th
  • • 11:00-11:25 "Responsive Probe to Detect Glutamate Changes by MRI - Mishra
    • 11:25-11:50 "Yb-HPDO3A: how to exploit conformational isomers to design concentration independent responsive paraCEST probes - Daniela Delli Castelli
    • 11:50-12:15 "Mn(II) complexes as alternative Contrast Agents for MRI" - Drahos
    • 12:15-12:40 "Synthesis and copper complexation of some cyclic bis-aminomethyl-phosphinic acid derivatives - Gyula Tircso
  • 12:45 -14:30 Lunch
  • Chairman: David Parker
  • • 14:30-14:55 "Functional gold nanoparticles for use in luminescent sensing and imaging" - Jon Kitchen
    • 14:55-15:20 "Liposomes and Lipoproteins as bimodal imaging probes" - Sara Lacerda
    • 15:20-15:45 "Phosphonate-TiO₂ Assamblies: Platform for Multimodal Diagnostic-Therapeutic Nanoprobes" - Rehor
    • 15:45-16:10 "Isoquinoline-based Lanthanide Complexes as Bimodal Probes for Magnetic Resonance and Optical Imaging" - Caille
  • 16:10-16:35 Coffee Break
  • Chairman: C. Geraldes/G. Angelovski
  • • 16:35-18:30 Poster Session (short presentations)
  • 20:00 Social Dinner
  
  
• SATURDAY, 26^th March 2011
• • Chairman: Ivan Lukes
  • • 9:30-9:55 "Controlling amide substituent conformation in LnDOTA-tetraamide chelates: Implications for paraCEST design - Mark Woods
    • 9:55-10:20 "Improving the relaxivity of Gd(III)-silica nanoparticles conjugates" - Lorenzo Tei
    • 10:20-10:45 "Novel Gd (III) Chelate Appended Quantum Dots: Dual-Modal and Multimeric MRI Contrast Agents" - Graeme Staesiuk
  • 10:45-11:15 Coffee Break
  • Chairman: Mauro Botta/Enzo Terreno
  • • 11:15-11:40 "MRI Contrast Agents for Sensing Neurotransmitters - Fatima Oukhatar
    • 11:40-12:30 Plenary II
      "CE-MRI beyond perfusion: on the route towards molecular imaging applications" - Alessandro Maiocchi (Bracco Imaging SpA)
  • 12:30-12:50 Closing remarks
  • 13:00 Lunch

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