Molecular Imaging Center
The Molecular Imaging Center (CIM) at the University of Torino, directed by Silvio Aime, is a cross-disciplinary chemistry and life science lab. Our work at the CIM is to develop imaging probes that support preclinical research with focus in several life science areas. It was founded by a joined initiative of chemists, biologists and physicians approved by the Italian Ministry of University and Research in 2001.
Currently, the CIM is an international imaging science center equipped with state-of-the-art imaging instrumentations covering all the available imaging modalities as well as multimodality imaging.
Since 2016, it coordinates the activities of the Euro-BioImaging multi-sited "Multi-Modal Molecular Imaging Italian Node" (MMMI), which offers access to Molecular Imaging technologies and related services to national and trans-national reasearchers. Users can access our services at a discounted rate by applying at the Euro-BioImaging Web Access Portal. More info on the MMMI Node website.
Research Areas
News and Events
Euro-BioImaging
European Commission launched the Euro-Bioimaging ERIC
Italian Multi-sited Multi-Modal Molecular Imaging (MMMI) Node Candidate
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COST Actions
COST Actions CA15209 - Eurelax"European Network on NMR Relaxometry"
COST Actions CA16103 - Parenchima
"Magnetic Resonance Imaging Biomarkers for Chronic Kidney Disease"
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Ongoing Projects
CIM partecipates to the H2020 project GLINT aimed to investigate GlucoCESt imaging as a potentially disruptive new diagnostic tool.
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CIM partecipates to the H2020 project IDENTIFY aimed to bring Fast Field-Cycling MRI (FFC-MRI) to the stage where it can be used as a routine tool for clinical diagnosis.
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In vitro and in vivo BNCT investigations using a carborane containing sulfonamide targeting CAIX epitopes on malignant pleural mesothelioma and breast cancer cells.
Geninatti Crich S et al;Sci Rep 10, 19274 (2020)
A novel class of 1H-MRI Contrast Agents based on the relaxation enhancement induced on water protons by 14N imidazole moieties.
Geninatti Crich S et al;Angew. Chem. Int. Ed. Accepted
Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH.
Longo D. et al;Cancer Metastasis Rev. 2019 Feb 14.
Gadolinium presence, MRI hyperintensities, and glucose uptake in the hypoperfused rat brain after repeated administrations of gadodiamide.
Gianolio E. et al;Neuroradiology. 2018
Indocyanine Green labeling for optical and photoacoustic imaging of Mesenchymal Stem Cells after in vivo transplantation.
Terreno E. et al;J Biophotonics. 2018
Efficient Route to Label Mesenchymal Stromal Cell-Derived Extracellular Vesicles.
Geninatti S. et al;ACS Omega. 2018 Jul 31;3(7):8097-8103.
Metabolic Studies of Tumor Cells Using [1-13 C] Pyruvate Hyperpolarized by Means of PHIP-Side Arm Hydrogenation.
Reineri F. et al;Chemphyschem. 2018, 19, 1-9.
[Yb(AAZTA)(H2O)]-: an unconventional ParaCEST MRI probe.
Delli Castelli D. et al;Chem Commun. 2018 Feb 20;54(16):2004-2007.
An efficient MRI agent targeting extracellular markers in prostate adenocarcinoma.
Stefania R et al;Magn Reson Med. 2018; 1-12
Cancer cell death induced by ferritins and the peculiar role of their labile iron pool.
Cutrin JC et al;Oncotarget. 2018 Jun 15; 9(46): 27974-27984
