Research

The Molecular Imaging Center brings together scientists who share a common interest in developing imaging probes and protocols and exploiting using state-of-the-art imaging technology for studying important biological-related issues.

Probes development at CIM:

Probe synthesis
PI: Stefania, Tei
Gd-complexes
PI: Terreno, Gianolio, Longo
CEST contrast agents
Graphic representing DIACEST, PARACEST and LIPOCEST agents PI: Terreno, Delli Castelli, Longo, Ferrauto
Hyperpolarized agents
PI: Reineri
Multi-modality agents
PI: Terreno
Responsive agents
PI: Longo, Delli Castelli, Gianolio, Digilio, Ferrauto
Nanosized and Targeting agents
PI: Terreno, Geninatti Stefania, Ferrauto
Theranostic agents
PI: Terreno, Geninatti, Cutrin
19F based contrast agents
PI: Terreno, Dastrù, Delli Castelli, Menchise
Gd−boron agents for NCT
PI: Geninatti
Photoacoustic probes
PI: Longo, Ferrauto

Main lines of research activity at CIM:

Cell labeling and tracking
Scheme representing negative Gd-containing particles electrostatically bonded to cationic polypeptide chains sorrounding a cell PI: Terreno, Geninatti, Ferrauto
Tumor angiogenesis
Scheme representing neoangiogenic vessels connecting a tumor mass to a main vessel PI: Longo
Tumor acidosis
Scheme representing some of the methabolism involved in tumor acidosis PI: Longo, Delli Castelli, Ferrauto
Tumor metabolism
Scheme representing tumor metabolism PI: Reineri
Inflammation & Infectious Diseases
PI: Cutrin
Imaging & Therapy
PI: Terreno, Geninatti, Cutrin
Imaging enzymatic activity
Scheme representing the action of an enzyme to form a product by connecting two substrates togheter PI: Digilio, Reineri
In vivo FFC relaxometry
PI: Geninatti, Gianolio
Gadolinium deposition
PI: Gianolio
Image Processing
PI: Dastrù, Longo