Dario Longo is author of more than 60 papers in peer-reviewed journals and of four book chapters.
Full list of publications are available at PubMed , Scopus or at Google Scholar.

Journal Papers

    |2021

  1. Villano, Daisy; Romdhane, Feriel; Irrera, Pietro; Consolino, Lorena; Anemone, Annasofia; Zaiss, Moritz; Dastru, Walter; Longo, Dario Livio "A Fast Multislice Sequence for 3D MRI-CEST pH Imaging" Magnetic Resonance in Medicine, 2021, 85, 1335

  2. |2020

  3. Martina Capozza, Rachele Stefania, Luisa Rosas, Francesca Arena, Lorena Consolino, Annasofia Anemone, James Cimino, Dario Livio Longo and Silvio Aime "An Improved Biocompatible Probe for Photoacoustic Tumor Imaging Based on the Conjugation of Melanin to Bovine Serum Albumin" Applied Sciences 2020, 10, 8313

  4. Grunewald, Thomas G. P.; Alonso, Marta; Avnet, Sofia; Banito, Ana; Burdach, Stefan; Cidre-Aranaz, Florencia; Di Pompo, Gemma; Distel, Martin; Dorado-Garcia, Heathcliff; Garcia-Castro, Javier; Gonzalez-Gonzalez, Laura; Grigoriadis, Agamemnon E.; Kasan, Merve; Koelsche, Christian; Krumbholz, Manuela; Lecanda, Fernando; Lemma, Silvia; Longo, Dario Livio; Madrigal-Esquivel, Claudia; Morales-Molina, Alvaro; Musa, Julian; Ohmura, Shunya; Ory, Benjamin; Pereira-Silva, Miguel; Perut, Francesca; Rodriguez, Rene; Seeling, Carolin; Al Shaaili, Nada; Shaabani, Shabnam; Shiavone, Kristina; Sinha, Snehadri; Tomazou, Eleni M.; Trautmann, Marcel; Vela, Maria; Versleijen-Jonkers, Yvonne M. H.; Visgauss, Julia; Zalacain, Marta; Schober, Sebastian J.; Lissat, Andrej; English, William R.; Baldini, Nicola; Heymann, Dominique "Sarcoma treatment in the era of molecular medicine" EMBO Molecular Medicine, 2020, 12, e11131

  5. Hao Wu, Veronica Estrella, Matthew Beatty, Dominique Abrahams, Asmaa El-Kenawi, Shonagh Russell, Arig Ibrahim-Hashim, Dario Livio Longo, Yana K. Reshetnyak, Anna Moshnikova, Oleg A. Andreev, Kimberly Luddy, Mehdi Damaghi, Krithika Kodumudi, Smitha R. Pillai, Pedro Enriquez-Navas, Shari Pilon-Thomas, Pawel Swietach, Robert J. Gillies "T cells produce acidic niches in lymph nodes to suppress their effector functions" Nature Communications, 2020, 11, 4113

  6. Federica Riccardo, Giuseppina Barutello, Angela Petito, Lidia Tarone, Laura Conti, Maddalena Arigoni, Chiara Musiu, Stefania Izzo, Marco Volante, Dario Livio Longo, Irene Fiore Merighi, Mauro Papotti, Federica Cavallo, Elena Quaglino "Immunization against ROS1 by DNA electroporation impairs K-Ras-driven Lung Adenocarcinomas" Vaccines, 2020, 8, 166

  7. Pietro Irrera, Lorena Consolino, Juan Carlos Cutrin, Frank G. Zollner, Dario Livio Longo "Dual assessment of kidney perfusion and pH by exploiting a dynamic CEST-MRI approach in an acute kidney ischemia reperfusion injury murine model" NRM in Biomedicine, 2020, 33, e4287

  8. Consolino L, Anemone A, Capozza M, Carella A, Irrera P, Corrado A, Dhakan C, Bracesco M, Longo DL "Non-invasive Investigation of Tumor Metabolism and Acidosis by MRI-CEST Imaging" Frontiers in Oncology, 2020, 10, 161

  9. |2019

  10. L. Granato, DL. Longo, S. Boutry, L. Vander Elst, C. Henoumont, S. Aime, R.N. Muller, S. Laurent "Synthesis and relaxometric characterization of new Poly[N,N-bis(3AminoPropyl)Glycine] (PAPGly) dendrons Gd-based contrast agents and their in-vivo study by using the Dynamic Contrast-Enhanced MRI technique at Low field (1 T)" Chemistry & Biodiversity, 2019, 16, e1900322

  11. Cohen G, Hadas R, Stefania R, Pagoto A, Ben-Dor S, Kohen F, Longo DL, Elbaz M, Dekel N, Gershon E, Aime S, Neeman M "MRI reveals distinct roles for tissue transglutaminase and factor XIII in maternal angiogenesis during early mouse pregnancy" Arteriosclerosis, Thrombosis, and Vascular Biology. 2019, 39, 1602

  12. Anemone A, Consolino L, Arena F, Capozza M, Longo DL "Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH" Cancer Metastasis Rev. 2019, 38, 25

  13. Kujawa A, Kim M, Demetriou E, Anemone A, Longo DL, Zaiss M, Golay X. "Assessment of a clinically feasible Bayesian fitting algorithm using a simplified description of Chemical Exchange Saturation Transfer (CEST) Imaging" Journal of Magnetic Resonance, 2019, 300, 120

  14. Pagoto A, Tripepi M, Stefania R, Lanzardo S, Longo DL, Garello F, Porpiglia F, Manfredi M, Aime S, Terreno E. "An efficient MRI agent targeting extracellular markers in prostate adenocarcinoma" Magnetic Resonance in Medicine 2019, 81, 1935

  15. Zaiss M, Anemone A, Goerke S, Longo DL, Herz K, Pohmann R, Aime S, Rivlin M, Navon G, Golay X, Scheffler K "Quantification of hydroxyl exchange of D-Glucose at physiological conditions for optimization of glucoCEST MRI at 3T, 7T and 9.4 T" NMR in Biomedicine, 2019, 32, e4113

  16. |2018

  17. Wu Y, Zhou IY, Igarashi T, Longo DL, Aime S, Sun PZ. "A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol" Magn Reson Med. 2018,79 1553

  18. Srivastava K, Ferrauto G, Harris S, Longo DL, Botta M, Aime S, Pierre V. "Complete On/Off Responsive ParaCEST MRI Contrast Agents for Copper and Zinc" Dalton Transactions 2018, 47, 11346

  19. Goerke S, Breitling J, Zaiss M, Windschuh J, Kunz P, Schuenke P, Paech D, Longo DL, Klika KD, Ladd ME, Bachert P. "Dual-frequency irradiation CEST-MRI of endogenous bulk mobile proteins" NMR in Biomedicine 2018, 31, e3920

  20. Wyart E, Reano S, Hsu MY, Longo DL, Li M, Hirsch E, Filigheddu N, Ghigo A, Riganti C, Porporato PE. "Metabolic Alterations in a Slow-Paced Model of Pancreatic Cancer-Induced Wasting" Oxidative Medicine and Cellular Longevity 2018, in press

  21. Arena F, Irrera P, Consolino L, Colombo Serra S, Zaiss M, Longo DL. "Flip-angle based ratiometric approach for pulsed CEST-MRI pH imaging" J Magn Reson. 2018, 287, 1

  22. |2017

  23. Anemone A, Consolino L, Conti L, Reineri F, Cavallo F, Aime S, Longo DL. "In vivo evaluation of tumour acidosis for assessing the early metabolic response and onset of resistance to dichloroacetate by using magnetic resonance pH imaging" Int J Oncol. 2017, 51, 498

  24. Longo DL, Moustaghfir FZ, Zerbo A, Consolino L, Anemone A, Bracesco M, Aime S. "Exploiting pharmaceutical excipients as MRI-CEST contrast agents for tumor imaging" Int J Pharm. 2017, 525, 275

  25. Longo DL, Stefania R, Aime S, Oraevsky A. "Melanin-Based Contrast Agents for Biomedical Optoacoustic Imaging and Theranostic Applications" Int J Mol Sci. 2017, 18, E1719

  26. Longo DL, Cutrin JC, Michelotti F, Irrera P, Aime S. "Noninvasive evaluation of renal pH homeostasis after ischemia reperfusion injury by CEST-MRI" NMR Biomed. 2017, 30, e3720

  27. Fagoonee S, Picco G, Orso F, Arrigoni A, Longo DL, Forni M, Scarfò I, Cassenti A, Piva R, Cassoni P, Silengo L, Tolosano E, Aime S, Taverna D, Pandolfi PP, Brancaccio M, Medico E, Altruda F. "The RNA-binding protein ESRP1 promotes human colorectal cancer progression" Oncotarget. 2017, 8, 10007

  28. Consolino L, Longo DL, Sciortino M, Dastrù W, Cabodi S, Giovenzana GB, Aime S. "Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging" Gastric Cancer. 2017, 20, 629

  29. Longo DL, Stefania R, Callari C, De Rose F, Rolle R, Conti L, Consolino L, Arena F, Aime S. "Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy" Adv Healthc Mater. 2017, 6, 1600550

  30. Anemone A, Consolino L, Longo DL. "MRI-CEST assessment of tumour perfusion using X-ray iodinated agents: comparison with a conventional Gd-based agent" Eur Radiol. 2017, 27, 2170
  31. |2016

  32. Longo DL, Bartoli A, Consolino L, Bardini P, Arena F, Schwaiger M, Aime S. "In vivo imaging of tumour metabolism and acidosis by combining PET and MRI-CEST pH imaging" Cancer Research 2016, 76, 6463

  33. Consolino L, Longo DL, Dastrù W, Cutrin JC, Dettori D, Lanzardo S, Oliviero S, Cavallo F, Aime S. "Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging" Int J Cancer. 2016, 139, 404

  34. Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-Crich S, Giovenzana GB, Aime S. "Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners" Biomaterials. 2016 , 75, 47

  35. Longo DL, Michelotti F, Consolino L, Bardini P, Digilio G, Xiao G, Sun PZ, Aime S. "In Vitro and In Vivo Assessment of Nonionic Iodinated Radiographic Molecules as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Tumor Perfusion Agents" Invest Radiol. 2016, 51, 155

  36. Mulas G, Anedda R, Longo DL, Roggio T, Uzzau S. "An MRI method for monitoring the ripening of Grana Padano cheese" International Dairy Journal 2016, 52, 19
  37. |2015

  38. Longo DL, Dastrù W, Consolino L, Espak M, Arigoni M, Cavallo F, Aime S. "Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment" Magn Reson Imaging. 2015, 33, 725

  39. Wu R, Longo DL, Aime S, Sun PZ. "uantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging" NMR Biomed. 2015, 28, 555

  40. Voena C, Menotti M, Mastini C, Di Giacomo F, Longo DL, Castella B, Merlo MEB, Ambrogio C, Wang Q, Minero VG, Poggio T, Martinengo C, D'Amico L, Panizza E, Mologni L, Cavallo F, Altruda F, Butaney M, Capelletti M, Inghirami G, Jänne PA, Chiarle R. "Efficacy of a Cancer Vaccine against ALK-Rearranged Lung Tumors" Cancer Immunol Res. 2015, 3, 1333

  41. Braccini L, Ciraolo E, Campa CC, Perino A, Longo DL, Tibolla G, Pregnolato M, Cao Y, Tassone B, Damilano F, Laffargue M, Calautti E, Falasca M, Norata GD, Backer JM, Hirsch E. "PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling" Nat Commun. 2015, 23, 7400

  42. Abate F, Todaro M, van der Krogt JA, Boi M, Landra I, Machiorlatti R, Tabbò F, Messana K, Abele C, Barreca A, Novero D, Gaudiano M, Aliberti S, Di Giacomo F, Tousseyn T, Lasorsa E, Crescenzo R, Bessone L, Ficarra E, Acquaviva A, Rinaldi A, Ponzoni M, Longo DL, Aime S, Cheng M, Ruggeri B, Piccaluga PP, Pileri S, Tiacci E, Falini B, Pera-Gresely B, Cerchietti L, Iqbal J, Chan WC, Shultz LD, Kwee I, Piva R, Wlodarska I, Rabadan R, Bertoni F, Inghirami G; European T-cell Lymphoma Study Group. " A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation" Leukemia. 2015, 29, 1390
  43. |2014

  44. Longo DL, Sun PZ, Consolino L, Michelotti FC, Uggeri F, Aime S. "A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with iobitridol" J Am Chem Soc. 2014, 136, 14333

  45. Perino A, Beretta M, Kilić A, Ghigo A, Carnevale D, Repetto IE, Braccini L, Longo DL, Liebig-Gonglach M, Zaglia T, Iacobucci R, Mongillo M, Wetzker R, Bauer M, Aime S, Vercelli A, Lembo G, Pfeifer A, Hirsch E. "Combined inhibition of PI3Kβ and PI3Kγ reduces fat mass by enhancing α-MSH-dependent sympathetic drive" Sci Signal. 2014, 7, ra110

  46. Riccardo F, Arigoni M, Buson G, Zago E, Iezzi M, Longo DL, Carrara M, Fiore A, Nuzzo S, Bicciato S, Nanni P, Landuzzi L, Cavallo F, Calogero R, Quaglino E. "Characterization of a genetic mouse model of lung cancer: a promise to identify Non-Small Cell Lung Cancer therapeutic targets and biomarkers" BMC Genomics. 2014, 15 Suppl 3:S1

  47. Sun PZ, Longo DL, Hu W, Xiao G, Wu R. "Quantification of iopamidol multi-site chemical exchange properties for ratiometric chemical exchange saturation transfer (CEST) imaging of pH" Phys Med Biol. 2014, 59, 4493

  48. Longo DL, Di Gregorio E, Abategiovanni R, Ceccon A, Assfalg M, Molinari H, Aime S. "Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour" Analyst. 2014, 139, 2687
  49. |2013

  50. Bandini S, Curcio C, Macagno M, Quaglino E, Arigoni M, Lanzardo S, Hysi A, Barutello G, Consolino L, Longo DL, Musiani P, Forni G, Iezzi M, Cavallo F. "Early onset and enhanced growth of autochthonous mammary carcinomas in C3-deficient Her2/neu transgenic mice" Oncoimmunology. 2013, 2, e26137

  51. Avedano S, Botta M, Haigh JS, Longo DL, Woods M. "Coupling fast water exchange to slow molecular tumbling in Gd3+ chelates: why faster is not always better" Inorg Chem. 2013, 52, 8436

  52. Castelli DD, Terreno E, Longo DL, Aime S. "Nanoparticle-based chemical exchange saturation transfer (CEST) agents" NMR Biomed. 2013, 26, 839

  53. Ceccon A, D'Onofrio M, Zanzoni S, Longo DL, Aime S, Molinari H, Assfalg M. "NMR investigation of the equilibrium partitioning of a water-soluble bile salt protein carrier to phospholipid vesicles" Proteins. 2013, 81, 1776

  54. Casalini F, Fugazza L, Esposito G, Cabella C, Brioschi C, Cordaro A, D'Angeli L, Bartoli A, Filannino AM, Gringeri CV, Longo DL, Muzio V, Nuti E, Orlandini E, Figlia G, Quattrini A, Tei L, Digilio G, Rossello A, Maiocchi A. "Synthesis and preliminary evaluation in tumor bearing mice of new (18)F-labeled arylsulfone matrix metalloproteinase inhibitors as tracers for positron emission tomography" J Med Chem. 2013, 56, 2676

  55. Longo DL, Busato A, Lanzardo S, Antico F, Aime S. "Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent" Magn Reson Med. 2013, 70, 859

  56. Geninatti Crich S, Alberti D, Orio L, Stefania R, Longo DL, Aime S. "Lipid-Based Nanoparticles in Cardiovascular Molecular Imaging" Current Cardiovascular Imaging Reports 2013, 6, 69
  57. |2012

  58. Arigoni M, Barutello G, Lanzardo S, Longo DL, Aime S, Curcio C, Iezzi M, Zheng Y, Barkefors I, Holmgren L, Cavallo F. "A vaccine targeting angiomotin induces an antibody response which alters tumor vessel permeability and hampers the growth of established tumors" Angiogenesis. 2012, 15, 305
  59. |2011

  60. Geninatti-Crich S, Szabo I, Alberti D, Longo DL, Aime S. " MRI of cells and mice at 1 and 7 Tesla with Gd-targeting agents: when the low field is better!" Contrast Media Mol Imaging. 2011, 6, 421

  61. Dastrù W, Longo DL, Aime S. "Contrast agents and mechanisms" Drug Discov Today Technol. 2011, 8, e109

  62. Longo DL, Dastrù W, Digilio G, Keupp J, Langereis S, Lanzardo S, Prestigio S, Steinbach O, Terreno E, Uggeri F, Aime S. "Iopamidol as a responsive MRI-chemical exchange saturation transfer contrast agent for pH mapping of kidneys: In vivo studies in mice at 7 T" Magn Reson Med. 2011, 65, 202

  63. Botta M, Avedano S, Giovenzana GB, Lombardi A, Longo DL, Cassino C, Tei L, Aime S. "Relaxometric Study of a Series of Monoaqua GdIII Complexes of Rigidified EGTA-Like Chelators and Their Noncovalent Interaction with Human Serum Albumin" Eur J Inorg Chem 2011, 6, 802
  64. |2010

  65. Tei L, Mazooz G, Shellef Y, Avni R, Vandoorne K, Barge A, Kalchenko V, Dewhirst MW, Chaabane L, Miragoli L, Longo DL, Neeman M, Aime S. "Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity" Contrast Media Mol Imaging. 2010, 5, 213

  66. de Leva MF, Filla A, Criscuolo C, Tessa A, Pappatà S, Quarantelli M, Bilo L, Peluso S, Antenora A, Longo DL, Santorelli FM, De Michele G. "Complex phenotype in an Italian family with a novel mutation in SPG3A" J Neurol. 2010, 257, 328

  67. Terreno E, Dastrù W, Castelli DD, Gianolio E, Crich SG, Longo DL, Aime S. "Advances in Metal-Based Probes for MR Molecular Imaging Applications" Curr Med Chem. 2010, 17, 3684
  68. |2009

  69. Terreno E, Stancanello J, Longo DL, Castelli DD, Milone L, Sanders HM, Kok MB, Uggeri F, Aime S. "Methods for an improved detection of the MRI-CEST effect" Contrast Media Mol Imaging. 2009, 4, 237

  70. Francalanci F, Avolio M, De Luca E, Longo DL, Menchise V, Guazzi P, Sgrò F, Marino M, Goitre L, Balzac F, Trabalzini L, Retta SF. "Structural and functional differences between KRIT1A and KRIT1B isoforms: a framework for understanding CCM pathogenesis" Exp Cell Res. 2009, 315, 285

  71. Baroni S, Pariani G, Fanali G, Longo DL, Ascenzi P, Aime S, Fasano M. "Thermodynamic analysis of hydration in human serum heme-albumin" Biochem Biophys Res Commun. 2009, 385, 385
  72. |2007

  73. Avedano S, Tei L, Lombardi A, Giovenzana GB, Aime S, Longo DL, Botta M. "Maximizing the relaxivity of HSA-bound gadolinium complexes by simultaneous optimization of rotation and water exchange" Chem Commun (Camb) 2007, 7, 4726

  74. Carrera C, Digilio G, Baroni S, Burgio D, Consol S, Fedeli F, Longo DL, Mortillaro A, Aime S. "Synthesis and characterization of a Gd(III) based contrast agent responsive to thiol containing compounds" J Dalton Trans 2007, 21, 4980

  75. Gianolio E, Giovenzana GB, Longo DL, Longo I, Menegotto I, Aime S. "Relaxometric and modelling studies of the binding of a lipophilic Gd-AAZTA complex to fatted and defatted human serum albumin" Chem Eur J 2007, 13, 5785
  76. |2005

  77. Aime S, Gianolio E, Longo DL, Pagliarin R, Lovazzano C, Sisti M. "New insights for pursuing high relaxivity MRI agents from modelling the binding interaction of Gd(III) chelates to HSA" Chembiochem. 2005, 6, 818

  78. Geninatti Crich S, Barge A, Battistini E, Cabella C, Coluccia S, Longo DL, Mainero V, Tarone G, Aime S. "Magnetic resonance imaging visualization of targeted cells by the internalization of supramolecular adducts formed between avidin and biotinylated Gd3+ chelates" J Biol Inorg Chem 2005, 10, 78
  79. |2004

  80. Ermondi G, Caron G, Lawrence R, Longo DL. "Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis" J Comput Aided Mol Des. 2004, 18, 683

Book Chapters